R-R intervals Variability and continuous Blood Pressure testing

Real-Time Monitor of R-R Intervals Variability analysis

Intellewave HRV system is a fully automated cardiac monitoring device that provides a quantitative assessment of Heart Rate Variability analysis. IntelleWave testing allows physicians to monitor physiological activity and assess the state of a patient’s autonomic function through analysis of Spectral Function Components of R-R intervals Variability. HRV testing with IntelleWave system enables physicians to detect specific types of autonomic dysfunction that may be linked to a multitude of clinical diagnoses. Additionally, IntelleWave is a tool for overall, general assessment of a patient’s physiology, and as such, provides a comprehensive, in-depth patient evaluation, often missing in standard medical practice. Such an ability to assess one’s physiology determines the wide range of IntelleWave’s clinical applications and distinguishes it favorably from all other diagnostic devices based on HRV analysis.  Moreover, IntelleWave can monitor HRV activity by providing of “real-time” quantitative assessment of spectral function components of HRV (HF and LF). Note: all clinical correlations of HRV analysis data are performed solely by a physician. IntelleWave system’s proprietary algorithm (US Patent 7,826,892 B2) uses novel artificial intelligence techniques to differentiate between Integrated HF and Integrated LF components of spectral function, where is Integrated HF and Integrated LF represent the most possible modulation of PSNS and SNS activity on all spectral function components. Artificial intelligence algorithm recognize this 2 new parameters after analysis of intercorrelations between of all spectral function components. This unique representation of test results allows physicians to recognize up to 81 different variations of the relationship between Integrated LF and Integrated HF components as an projection of SNS and PSNS activity. Intellewave also can provide “real-time” up to 24hr quantitative monitor of Integrated HF and Integrated LF activities level. The list of the potential application by this regime is next:
– Monitor Integrated HF and Integrated LF activity during anesthesia.
– Monitor Integrated HF and Integrated LF activity in intensive care to see the effectiveness of the medication.
– Monitor Integrated HF and Integrated LF activity by implantable devices.
– Using for sleep studies to see the difference between “sleep
time”  and “awake time”, also as a new features in Holter-Monitor technology.

Clusterization of the relationship between SNS and PSNS status

This technological breakthrough is achieved by using proprietary algorithms and a new approach based on one of the leading theories of Artificial Intelligence – Marvin Minsky’s Frame Theory. Intellewave objectively and reliably evaluates the state of ANS in “real-time” (up to 24 hours) as well as during Orthostatic test and Valsalva maneuver combined with Deep Breathing. Due to its highly sophisticated HRV analysis, Intellewave is the only system that enables quantification of 81 ANS states with a corresponding qualitative description for each one. Clusterization of the Autonomic Nervous System's States

Alexander Riftine

President & CEO

Vic Pershin

Technical Support

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